The Up-Down Reader software allows for the efficient processing of 50% von Frey thresholds based on the up-down method for 2 species (mouse, rat) and 2 forms of stimulus (plantar, visceral).

Given a PDF input, the software identifies and extracts the grid of von Frey assessment tables, recognizes the handwritten sequences entered in each of them, and computes the 50% response thresholds according to the selected species and stimulus. The computed values for each animal is reported on the interface; the output can be saved to a csv file.

How to fill the templates? Explanatory video: Watch in Youtube

Up–Down Reader: An Open Source Program for Efficiently Processing 50% von Frey Thresholds Full article

TO CITE OUR WORK: Gonzalez-Cano R, Boivin B, Bullock D, Cornelissen L, Andrews N, Costigan M. Up-Down Reader: An Open Source Program for Efficiently Processing 50% von Frey Thresholds. Front Pharmacol. 2018;9:433.